New hope for diagnosing chronic fatigue, a low recognized disease in India

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New hope for diagnosing chronic fatigue, a low recognized disease in India

New hope for diagnosing chronic fatigue, a low recognized disease in India

Researchers have identified some biomarkers who can help diagnose chronic fatigue syndrome with promising accuracy. This study can improve the recognition and treatment of chronic fatigue, especially in India where awareness is low.

Girl unhappy in a bedroom
Contrary to regular fatigue that improves after a good night sleep, CFS dries you even after rest hours. (Photo: Getty Image)

In short

  • Chronic fatigue syndrome causes persistent fatigue despite comfort
  • Symptoms include brain fog, muscle pain and sleep disturbances
  • Researchers have developed a biomarker detection blood test to better diagnose the condition.

If you are feeling tired for weeks or months, even after a lot of rest, it can only be more than stress or anemia. In fact, it is one of the most incorrect and under-dystrosed conditions called chronic fatigue syndrome (CFS), also known as melgic encephalomyelitis (ME/CFS), a complex and low-recognized disease that affects women more often than men, but is often missing for other conditions.

Contrary to regular fatigue that improves after a good night sleep, CFS dries you even after rest hours.

“CFS goes beyond normal fatigue or burnout. The fatigue persists or deteriorates after relaxation, and even minimal physical or mental efforts can increase symptoms, a condition called post-expiral illness,” Neurology, Neurology, Neurology in PSRI Hospital, said by Neurology.

Other symptoms may include disturbing sleep, brain fog, muscle and joint pain, sore throat, swollen lymph nodes, headaches, and poor concentration.

Because these symptoms overlap with depression, thyroid problems, post-viral syndromes and other diseases, many people also go for months-even without years of diagnosis for years.

“There are no definite laboratory tests to diagnose CFS. It is usually a diagnosis of exclusion, which means that the doctor is out of other conditions,” Dr. Ramanujam explained.

A new hope for diagnosis

Researchers at Cornell University have found a possible way to detect me/CFS using cell-free RNA, these are small marks of genetic material left in the blood when cells die.

These RNA pieces act as a “activity log”, which reveal changes in immune system, tissue injury, and other processes.

By analyzing these pieces and applying the machine-learning model, the team identified the major biomarckers that separate CFS patients from healthy individuals.

“We have taken a concrete steps towards a test for my/CFS,” we have taken a concrete steps towards a test for my/CFS, “said,” The cells that leave molecular fingers in the blood by reading the molecular fingers, the Associate Professor of Biomedical Engineering at Cornell.

In the study, published in the proceedings of the National Academy of Sciences, blood samples from CFS patients showed symptoms of laxity of the immune system, including changes in plasmastoid dendritic cells, which are immune cells associated with antiviral reactions and T cell exhaustion.

The test currently detects CFS with 77% accuracy. While not right, it is a promising step towards a long -awaited clinical tool.

Awareness matters in India

In India, fatigue in women is often attributed to iron deficiency or anemia, and supplements are determined without discovery of other reasons.

This can delay a CFS diagnosis. While the US and Britain have recognized and studied the situation on a large scale, even offering disability benefits, there is no official estimate in India, no dedicated research funding and little clinical awareness.

The CDC estimates that 836,000 to 2.5 million Americans have CFS, which costs the US economy $ $ 9 to $ 25 billion annually in lost productivity and healthcare.

In India, many patients are unknowingly, unknown and sometimes dismissed as “lazy” or “overseas”.

Stay with CFS

The exact cause of CFS is still unknown, but experts believe that it may be triggered by viral infection, immune or hormonal imbalance, or extreme stress.

There is no cure, but the treatment focuses on managing symptoms and improving the quality of life, including activity pacing (avoiding oversials), better sleep hygiene, pain management, good nutrition and stress reduction and even cognitive behavior therapy.

Most importantly, patients need to listen and feel valid.

As Dr. Ramanujam insisted, “CFS is real. Identifying and understanding it can create a world of differences for those living with it.”

– Ends

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