Childhood contact for a bacterial toxin in the colon can trigger an increase in colorectal cancer cases in young patients, showing a new study.

Once the disease of chronic adults is considered, colorectal cancer is now growing among young people in at least 27 countries. Its incident in adults under 50 has almost doubled in every decade for the last 20 years.

In search of clues for this, why, researchers analyzed the genes of 981 colorectal cancer tumors from patients with different colorectal cancer risk to the early or late starting disease in 11 countries.

DNA mutation in colon cells, which is to be caused by a toxin produced by ascarichia coli, called colibactin, was 3.3 times more common in adults who developed colon cancer before the age of 70 years of age.

The pattern of mutation is raised when children are exposed to colibalabactin before the age of 10, the researchers explained in nature.

The mutation patterns were particularly prevalent in countries with high phenomena of initial start cases.

UC San Diego leader Ludmil Alexandrov said in a statement, “If someone receives one of them … Mutation, they can be decades before the schedule for the development of colorectal cancer, they can get it at the age of 40,” he can get it at 40 years of age, “the study leader of UC San Diego said in a statement in a statement.

Alexandrov said, “Not every environmental factor or behavior has been studied, which leaves a mark on our genome.” “But we have found that Colibactin is one of those who can do. In this case, its genetic impression appears to be firmly associated with colorectal cancer in young adults.”

Researchers have found other mutual signatures in colorectal cancer in specific countries, especially Argentina, Brazil, Columbia, Russia and Thailand.

This suggests that local environmental risk can also contribute to the risk of cancer, he said.

“It is possible that different countries have different reasons in different countries,” said Marcos Diaz-G, co-writer at the Spanish National Cancer Research Center in Madrid, in Madrid.

“It can open capacity for targeted, field-specific prevention strategies.”