Indian AI screens 1.1 billion molecules, makes anti-aging breakthrough

AgeXtend is a unique platform that uses data from existing anti-aging molecules to predict new anti-aging molecules. It also ensures their safety by checking for toxic effects.

AgeXtend is a unique platform that uses data from existing anti-aging molecules to predict new anti-aging molecules.
The AI ​​tool uses data from existing anti-aging molecules to predict new molecules. (Photo: Getty Images)

Researchers at Indraprastha Institute of Information Technology Delhi (IIIT-Delhi) have introduced AgeXtend, an artificial intelligence (AI)-powered platform designed to discover molecules that can slow down aging. and can promote healthy living.

This important breakthrough, published in the journal Nature Aging, offers hope for tackling aging and age-related health challenges.

AgeXtend is a unique platform that uses data from existing anti-aging molecules to predict new anti-aging molecules. It not only suggests potential candidates but also ensures their safety by examining toxic effects and understanding how they work in the body.

Researchers tested AgeXtend by excluding well-known compounds like metformin and taurine, molecules already known to extend lifespan, and found that the platform could still predict their benefits.

Researchers led by Sakshi Arora combined AI and biology to create EdgeXtend, making it easier to find solutions that can help people live longer and healthier lives.

The team screened more than 1.1 billion molecules and found several new promising candidates. To confirm their effectiveness, they were tested on yeast, small insects called C. elegans and human cells.

They used special experiments on human cells to test natural compounds found in the body that AgeXtend predicted could be molecules that could slow aging.

This revealed AgeXtend's potential to discover new anti-aging substances to help better understand how aging works.
This revealed AgeXtend’s potential to discover new anti-aging substances to help better understand how aging works. (Photo: Getty Images)

This revealed AgeXtend’s potential to discover new anti-aging substances to help better understand how aging works.

Dr. Gaurav Ahuja, a senior researcher on the project, said, “AgeXtend helps us predict anti-aging molecules and understand how they work. It is a powerful tool that could provide new insights into aging and related diseases.” “Can lead to treatment.”

Sakshi Arora, lead author of the study, called AgeXtend a “discovery engine” and highlighted its ability to detect aging in a way that had never been done before.

He said that this research is a big step towards improving health and longevity.

The study also highlights AgeXtend’s ability to analyze the human microbiome, the natural compounds found in the tiny organisms that live in our bodies, and their role in controlling cell aging.

This shows how versatile and innovative the platform is.

In the current anti-aging industry, where companies are claiming that various medications, drugs or pills can slow down aging, India’s new innovation AgeXtend is helping to better understand aging and help people live healthier, longer lives. Opens the door to finding practical solutions to do.

This makes it an unprecedented achievement in the field of aging research.

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