According to new research by the University of South Australia, over-the-counter painkillers such as Ibuprofen and Paracetamol can quietly promote one-antibiotic resistance among the world’s largest health hazards.

The first of its kind has been described as a study, researchers found that both of these usually use non-antibiotic drugs, when either taken or taken together, can increase the mutation of bacteria.

It, in turn, forms Eschherichia coli (E. coli), a bacteria that is often responsible for intestinal and urinary tract infections, more resistant to siprofloxacin, a broad spectrum antibiotic (which effectively kills many types of bacteria).

What did the researchers find?

The study led by Associate Professor Riti Venter showed that the presence of ibuprofen and paracetamol not only reduced the effectiveness of ciprofloxacin, but also increased resistance to many antibiotic classes.

“Antibiotics have long been important in treating infectious diseases, but their extensive exercises and misuse have increased the global growth in antibiotic-resistant bacteria. It is particularly related to residential aging care facilities, where older adults are often given many drugs resistant-only antibiotles resistant,” Dr. Ventator said, whose research paper published an antimicrobial and resistance to the magazine.

The World Health Organization (WHO) has classified antimicrobial resistance as a global public health threat, directly responsible for 1.27 million deaths worldwide in 2019.

While earlier research has mainly focused on antibiotic abuse, new studies suggest that the challenge is more complex, common non-antibiotic drugs are also playing a role.

Drugs

Researchers have ibuprofen (relief from an anti -incredible pain), diclofenac (an anti -provocative provocative), acetaminophen (paracetamol for pain and fever), tramdol (a strong pain for a strong pain medicine), ATORVSTAT (a holestrol for a strong pain drug), ATORVSTAT (levels of diabetes) (levels of diabetes) (levels of diabetes), furous (high blood pressure), furocemic (Used to treat sleep problems), and pseudophydrin (a decongstant).

He found that both Ibuprofen and Paracetamol activated bacterial defense mechanism, e. Enable the coli to expel antibiotics and make them less effective.

“When bacteria were in contact with siprofloxacin with these pain relievers, they developed more genetic mutations than being treated with antibiotics alone. Not only did he oppose Ciprofloxacin, but he also showed resistance to many unrelated antibiotics,” Dr. Venter told.

Conclusions hold major importance to aged care facilities, where polypharmacy is ideal.

Older inhabitants are more likely to prescribe long-term drugs for chronic conditions such as diabetes, hypertension, arthritis, and sleep disorders, along with antibiotics for infection.

Not to prevent painkillers

Such a combination, studies shows the study, can accelerate the rise of resistant bacteria within the weak population.

Dr. Ventter insisted that the results should not be interpreted as a call to prevent the use of everyday pain reliever.

Instead, the study highlights the need for more awareness about potential drug interactions that can reduce antibiotic effectiveness.

“This does not mean that we should stop using these drugs, but we need to take more care about how they interact with antibiotics-and it involves looking beyond two-drug combinations,” Dr. Venter said.

Researchers have called for further investigation into drug interactions in long -term treatment governance. He highlighted that the fight against antibiotic resistance may no longer be restricted to monitor antibiotic misuse.