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Wet-loss drugs work, but here when weight starts returning

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Wet-loss drugs work, but here when weight starts returning

The new study suggests that weight loss drugs help during treatment but the weight returns rapidly after stopping. What did they find here.

Researchers show that weight loss returns after taking weight loss drugs. (Photo: Getty Image)
Researchers show that weight loss returns after taking weight loss drugs. (Photo: Getty Image)

In short

  • Weight starts to lose after eight weeks of stopping the medicine
  • Average of 2.5 kg after 20 weeks of treatment after weight gain
  • GLP-1 receptor agonists are associated with the most important rebound effect

Weight -loss drugs have become increasingly popular in India and the world. From bullets to new age injections, pharmaceutical giants are losing weight more than ever.

But a new research review has raised an important question: what happens after you stop taking them?

According to a new study published in BMC Medicine, many patients who lose weight on these drugs re -achieve it after closing it, and it can be early 8 weeks after closing.

Research saw the data of clinical trials conducted by around 2,500 participants. Of these, six studies focused on semaglutide, active components in popular drugs such as ozmpic and vegovi.

While these drugs helped the participants to lose weight during treatment, the benefits faded after stopping the drugs.

  • 4 weeks after stopping the drugs, there was no major change in weight compared to those who do not occur on the drug.
  • By 8 weeks, the participants began to gain weight compared to the control group, on average 1.5 kg.
  • In 12 weeks, the resin continued, an average 1.76 kg.
  • For 20 weeks, people achieved an average of 2.5 kg.

Wet Regen was the most noticeable among patients who were on GLP -1 receptor agonist drugs, such as semaglutide and tirzepetide, drugs of drugs that include vegovi and mounaro.

Researchers, Peking University, People’s Hospital, Chinese researchers say this may have a rebound effect because once the drugs are closed, the body’s hunger and metabolism come to their original state to return to their original state.

Many of these drugs work by mimicking hormones that regulate appetite and perfection, the effects that do not once occur after the drug is out of the system.

In addition, the study found that participants who followed the lifestyle changes (such as better diet and exercise) still gained weight after stopping the drug during treatment.

What does it mean for long -term weight management

Currently, six drugs are approved for the treatment of obesity in adults: Orlistat, Naltrexone-Bopropian, Semglutide, Liraglutide, Tiraglutide, Tirzepetide and Phentymin-Topiramate.

While these drugs are often effective for short -term weight loss, they are not a permanent solution by themselves.

Conclusions support the idea that anti-motor drugs should be seen as part of a broad, long-term strategy, including changes in lifestyle when necessary, behavior therapy and even bariatric surgery.

Doctors and patients should equally pay attention to the creation of permanent habits such as any medical treatment as well as nourishment, movement and stress management.

As researchers have said, more long -term studies are required to understand how to maintain weight loss after stopping these drugs.

– Ends

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