Assam experience in the highest events of gallbladder cancer in India.

While earlier studies have added high burden from factors such as arsenic-discounted water, a new study suggests that some types of bile stones, especially rich in cholesterol and heavy metals, can play an important role due to the most invasive forms of cancer in India.

Researchers at Tezpur University analyzed 40 bile stones taken from two groups of patients in Assam: 30 with gall bladder disease and 10 who had both gall bladder and gallstones.

They wanted to understand what some bile stones are more dangerous than others.

The gall bladder is a hard lump that is formed in the gallbladder, usually made of cholesterol or bile pigment and other substances such as calcium. While gall bladder disease is common, not all people with gallstones develop cancer.

The purpose of this study published in chemical research in toxic science is to find out why.

Scientists studied chemical and physical makeup of stones, using advanced equipment such as infrared light analysis, X-ray techniques and powerful microscope.

They found that most of the gall bladder in cancer patients were made of cholesterol and a crystal-like, layered structure-which was the same for the stack plates. This structure was more common in cancer group than people with gall bladder alone.

The presence of toxic elements in gallstones from cancer patients was even greater. These included arsenic, chromium, mercury, iron and lead – chemicals that are known to damage cells and potentially cause cancer.

These elements were found in high amounts of gallbladder cancer patients.

The study suggests that not only the presence of gallstones, but they can increase the risk of cancer.

Cholesterol -rich stone with these toxic metals create a more dangerous environment inside the gallbladder.

Scientists believe that high levels of these cancer -causing elements can come from environmental sources such as polluted water, food, or soil, especially in areas such as Assam where the gallbladder is higher.

This research highlights the urgent need to find out how cholesterol is processed in the body (called cholesterol disgusting) and how to contact to toxic metals can contribute to the rise of this fatal cancer.

The authors of the study stated that this can help people to identify high risk people, especially in areas such as Assam, and future preventive strategies.